| Meaning of 'Makrub' 'Makrub'
is an object noun whose origin is the verbal noun 'karb' meaning 'deep anguish'.
' Allama Tabataba'i in his al-Mizan quotes Raghib Isfahani, the famous lexicographer
of Qur'anic words, as saying57: 
Karb means deep anguish
The word Karbala, for example, is a composition
of 'intense grief (karb) and 'trial' (bala')
Therefore, in short, 'makrub'
is one who suffers deep sorrow and anguish.
The Source of Anguish
In this verse we are humbly asking Allah (swt) to lift the state of deep
anguish from all 'the deeply anguished and sorrowful'. And whosoever seeks the
relief of the anguished also seeks the elimination of the causes that create anguish
too. We should, however, realize that the sources of anguish vary according to
different people and different circumstances. Those who enjoy the proximity of
Allah, despite having no grief for loss of the world and its pleasures: 
Surely the Friends of Allah neither fear nor grieve [Holy Qur'an, 10:62]
experience
deep anguish for the disbelievers due to the outcomes they would have to face
in future: ____________________
57 'Allama Tabataba'i, AI-Mizan
fi Tafsiri'l Qur'an, v. 7, p. 134 | 
